Kin-Driver - A human kinase database with driver mutations



EGFR_HUMAN V689M  

UniProt Pfam

Validation Status: Activating

Relative Frequency: 0.0379262

Reference : EGFR database

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Central Moving Average Plot

Central Moving Average plot is not available as this mutation is not in the kinase domain.

3D Structures - Mapping the mutation onto a PDB structure

PDB idDescriptionResolutionSPACI Score
3GOP_Acrystal structure of the egf receptor juxtamembrane and kina2.80.267089
1Z9I_Aa structural model for the membrane-bound form of the juxtamembrane domain of the epidermal growth factor receptor0.00122381

PDB: 3GOP_A

Resolution: 2.8 Å
"crystal structure of the egf receptor juxtamembrane and kina"
UniProt residue Number PDB residue Number
689665
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